Central Research Laboratory
CENTRAL RESEARCH LABORATORY
Core Committees
Dr Jaishriram Rathored, Associate Professor and Incharge Molecular Diagnostics and Central Research Laboratory
Dr. Archana Dhok, Prof & HOD, Biochemistry : Member
Dr. Samarth Shukla, Vice Dean, JNMC : Member
List of Ongoing Research Projects 2024
| SN | Title of the project | Investigator |
| 1 | ICMR registry for rare diseases ICMR New Delhi (Haematology) |
Dr. Arvind Bhake Dr. Obaid Noman Department of Pathology, JNMC |
| 2 | Rifampicin extraction in Urine, estimation by HPLC | Shilpa Upadhyay Dr. Zahir Syed Quazi R & D, DMIMS(DU) |
| 3 | Comparative evaluation of polyherbal preparation as an adjuvant in metronomic chemotherapy in oral potentially malignant disease of moderate dysplasia – RCT | Dr. Rahul Bhowate Department of Oral Medicine & Radiology, SPDC |
| 4 | Gene polymorphism in ligamentous injury | Dr. Sanjay Deshpande Department of Orthopedics, JNMC |
| 5 | Standard drug release of Doxycycline and curcumin using electrospin nanofibers | Dr. Ashutosh Bagde Dr. Priyanka Banode, Dr. Zahir Quazi R & D |
| 6 | To Evauate dose dependent efficacy of antioxidant vit. C in relation to oxidative stress level in subjects with OSMF | Dr. Shraddha Patel Dr. Vidya Lohe Department of ODMR, SPDC |
| 7 | Assessment of efficacy of seasonal rutushodhan karma on oxidative stress in healthy volunteers | Dr. Pradnya Dandekar Dr. Vaishali Kuchewar Department of Kriyasharir, MGAC |
| 8 | Evaluation of effect of sharkara as anupana on the Bioavailability enhancer effect on Haritaki | Dr. Sneha Vidhate Dr. Dattatray Sarvade Department of Dravyaguna, MGAC |
| 9 | Evaluation and comparison of anxiety levels after using guided imagery technique for relaxation and modified guided imagery-hypnotherapy techniques in 6 to 14 year old children undergoing local anesthesia administration | Dr. Himani Parakh Dr. Nilima Thosar Department of pediatric and preventive Dentistry, SPDC |
| 10 | Evaluation of Anti-allergic activity of Panchashirishadi Agad in histamine induced allergy in Wistar rats | Dr. Shanti Manyala Dr. Sonali Chalakh Department of Agadtantra, MGAC |
| 11 | Comparative evaluation of novel Ca(OH)2 hydrogel with Ca(OH)2 iodofrom as obturating material : an in-vitro study | Dr. Dhruvi Raj Solanki Dr. Punit Fulzele Department of Pedodontics, SPDC |
| 12 | Comparative evaluation of Shatavari Ghanvati and Brahmi ghanavati in Senile Dementia | Dr. Mayuri Bawane Dr. Vaishali Kuchewar Department of kayachikitsa, MGAC |
| 13 | In vivo assessment of antihistaminic and anti-inflammatory action of Dooshivishari Agada | Dr. Sonali Chalakh Department of Agadtantra, MGAC |
| 14 | Study the effect of Nisha amalaki (as an adjuvant drug) in uncontrolled type II diabetes Mellitus – A Pragmatic controlled trial . | Dr. Shweta Parwe Department of Panchkarma MGAC |
| 15 | ABX-464-106 Study | Dr. Vijendra Kirnake Department of Gastroenterology, JNMC |
| 16 | Characterization and identification of molecular prevalence in Kleb P & E.coli. from the clinical isolates from tertiary care center | Dr. Radha Kunjalwar Dr. Gargi Mudey Department of Microbiology, JNMC |
| 17 | A Comparative study to evaluate Vrishya karma of Ustrakantaka (Echinops echinatus Roxb.) seeds versus roots on testicular regenerative property in wistar albino rats | Dr. Monika Dr. Rajkumar Gupta Department of Dravyaguna, MGAC |
| 18 | Pharmaceutical development and analysis of Tripatra Parpati and evaluation of its acute toxicity and antidiarrheal activity in wistar albino rats | Dr. Yogi Tajne Dr. Bharat Rathi Department of Rasshastra, MGAC |
| 19 | Identification and quantification of growth factors in the growth and development of cartilage present in exosomes of lactating mother’s blood of cleft infant as compared to non cleft infant – an analytical observational study | Dr. Nikita Soni Dr. Priyanka Niranjane Department of Orthodontics, SPDC |
| 20 | Comparison of Nephroprotective activity of Sairaiyak and Vipareetalajjaalu in Adriamycin induced nephrotoxicity in swiss albino rats – an animal study | Dr.Bhawana Mehra Dr. Jaymala Jadhav Department of Dravyaguna, MGAC |
| 21 | Evaluation of some herbal plants for diabetes induced Nephropathy | Ms. Jayshree Vyas Dr. Anita vanjari Department of Pharmacy, DMCP |
| JNMC | : 04 |
| SPDC | : 05 |
| MGAC | : 09 |
| R&D | 02 |
| DMCP | : 01 |
| OTHER | : 00 |
List of Completed Research Projects 2023
| Sr. No. | Title of the project | Investigator | Institution | Month of Completion |
| 1 | Serum Leptin levels, body mass index and its correlation with materno fetal outcome in gestational diabetes mellitus | Dr. Hard Tilva Dr. Surekha Tayade Department of OBGY, JNMC |
JNMC | January |
| 2 | Comparative HPTLC analysis of Pita Palash and Rakta Palash | Sakshi Mute Dr. Akshay Pargaonkar, Department of Dravyaguna, MGAC |
MGAC | January |
| 3 | Comparative HPTLC analysis of sprouted shimbi dhanya vs whole shimbi dhanya with special reference to Vigna aconitifolia Linn | Shreya Bonde Dr. Akshay Pargaonkar, Department of Dravyaguna, MGAC |
MGAC | January |
| 4 | Evaluation of immunomodulatory activity of Dhatryadi rasayana churna and its granules | Dr. Sheenam Rani Dr. Usha Sharma, Department of Rasshastra, MGAC Uttarakhand Ayurved University Haridwar |
Department of Rasshastra, Uttarakhand Ayurved University Haridwar | January |
| 5 | Assessment of Epidermal growth factor receptor signaling pathway in triple negative invasive ductal carcinoma of breast by molecular methods as a predictive marker | Dr. Sahitya Vodithala Dr. Arvind S. Bhake Department of Pathology, JNMC |
JNMC | February |
| 6 | Pharmaceutical analytical study of Vidarikandadi Churna and its modified dosage form and assessment of their comparative efficacy for strength, stamina and growth as compared to standard supplement in albino rats | Dr. Utkarsha Kandalkar Dr. Anita Wanjari Department of Rasshastra, MGAC |
MGAC | February |
| 7 | Air Duality monitoring project | Sukeshini Wankhede MGAC & RC |
MGAC & RC | February |
| 8 | Comparative efficiency of ginger extract gel with and without curcumin gel for management of homogeneous Leukoplakia evaluated by Salivary Malondialdehyde level (Biomarker) | Dr. Rakhi Chandak Dr. Vidya Lohe Department of ODMR, SPDC |
SPDC | March |
| 9 | Comparative evaluation of varaiations in clinical signs & symptoms in OSMF (Oral submucous fibrosis) patients with the use of polyherbal medication, therapeutic ultra sound & combination of polyherbal medication & therapeutic ultra sound | Dr. Mrunal Meshram Dr. V. K. Lohe Department of Oral Medicine & Radiology, SPDC |
SPDC | March |
| 10 | Assessment of solitary and combine effect of guduchi and punarnava on structural changes of aging in liver and kidney of wistar rat | Dr. Kalpana Tawalare Dr. Pradnya Dandekar Department of Rachana Sharir, MGAC |
MGAC | March |
| 11 | Comparative evaluation of efficacy of bromelain with MTA against the conventionally used MTA as direct pulp capping material. | Dr. Rashmi Chahande Dr. Pradnya Nikhade Department of conservative Dentistry & Endodontics, SPDC |
SPDC | April |
| 12 | Quantitative estimation of basic fibroblast growth factor in oral potentially malignant disorders and oral squamous cell carcinoma | Dr. Madhumita Chaudhari Dr. Alka Hande Department of Oral Pathology, SPDC |
SPDC | April |
| 13 | Comparative pharmaceutico-analytical study of Shilajatu collected from Himachal Pradesh with that samples obtained from standard commercial sources and their in-vitro antioxidant study | Dr. Sudarshan Kumar Thakur Dr. Bharat Rathi Department of Rasshastra, MGAC |
MGAC | April |
| 14 | Pharmaceutical development , standardization and clinical evaluation of efficacy of polyherbal hairpack and hairgel in dandruff control | Dr. Poonam Madan Dr. Bharat Rathi Department of Rasshastra, MGAC |
MGAC | April |
| 15 | Assessment of bonding of the total etch adhesive to carious dentin in molars treated with and without 38% silver diamine fluoride. | Dr. Joyeeta Mahapatra Dr. Pradnya Nikhade Department of Conservative Dentistry & Endodontics, SPDC |
SPDC | May |
| 16 | Evaluation of depth of penetration of four different irrigants using Ultrasonic activation protocol in Endodontic Microsurgery – a confocal laser scanning microscopic study | Dr. Disha Mehta Dr. Anuja Ikhar Department of Conservative Dentistry & Endodontics, SPDC |
SPDC | May |
| 17 | Formulation of development of cow-ghee based semisolid formulations of vitex negundo leaves extract for effective burn wound healing | Mrs. Monali Wawre Dr. Deepak Khobragade Department of Pharmacy |
DMCP | May |
| 18 | A comparative study on Ayurveda treatment modalities as de-addictive tools for addiction of tobacco products in school going children of Salod and Sawangi, Wardha | Dr. Renu Rathi Department of Kaumarabhritya, MGAC |
MGAC | June |
| 19 | Evaluating the efficacy of navkarshik kashay ghanvati & erandadi kashay ghanvati for its anti hyperuricemic activity | Dr. Kanika (PhD Scholar) Dr. Usha Sharma Uttarakhand |
Uttarakhand Ayurved University Haridwar | July |
| 20 | Assessment of variation in serum diamine oxidase, histamine and chymase levels in the various stages of OSMF, areca chewers without OSMF and healthy individuals by an ELISA | Dr. Harshkant Gharote Dr. Rahul Bhowate Department of ODMR, SPDC |
SPDC | July |
| 21 | Comparison of the efficacy of aescin and diclofenac sodium in the management of postoperative sequelac and their effect on salivary prostaglandin E2 and serum C-reactive protein levels after surgical removal of impacted mandibular third molar: a randomized, double-blind, controlled clinical trial | Dr. Anuroop Singhal Dr. Rajanikant Kanbala Department of ODMR, SPDC |
SPDC | July |
| 22 | Comparative evaluation of vitamin D supplement on bone turnover rate in vitamin D insufficient patients seeking orthodontic treatment using biomarkers | Dr. Megha Jain Dr. Ranjit Kamble Department of Orthodontics, SPDC |
SPDC | August |
| 23 | Evaluation of hepatoprotective activity of Nagdantyadi ghrita in paracetamol induced hepatotoxicity in wistar rats | Dr. Abhijeet Gawai Dr. Sonali Chalakh Department of Agadtantra, MGAC |
MGAC | August |
| 24 | Evaluating impact of biofilm on meropenem susceptibility and vice a versa in isolates of klebsiella pneumoniae & pseudomonas aeruginosa recovered from device associated Hospital acquired infections | Nilima Mistry Dr. Gargi Mudey Department of Microbiology, JNMC |
JNMC | Discontinued |
| 25 | Comparative evaluation of immunochromatographic test with ELISA for the diagnosis of dengue | Anita Manwatkar Dr. Mrinangka Deb Department of Microbiology, JNMC |
JNMC | Discontinued |
| 26 | Pharmaceutico analytical study of Gomutra Ghana & evaluation of its antimicrobial activity | Dr. Payal Raut Dr. Bharat Rathi Department of Rasshastra, MGAC |
MGAC | August |
| 27 | Pharmaceutical standardization and drug dosage modification of laghu sudarshan churna with comparative assessment of its antipyretic and analgesic activities in albino rats. | Dr. Mansi Chunchuwar Dr. Bharat Rathi Department of Rasshastra, MGAC |
MGAC | September |
| 28 | Pharmaceutical and analytical study of gandharva haritaki prepared by murchit and amurchit erand taila & comparative assessment for invitro bioavailability | Dr. Anjali Katore Dr. Anita Wanjari Department of Rasshastra, MGAC |
MGAC | September |
| 29 | Comparative evaluation of bromelain with biradentine & biodentine in isolation as direct pulp capping agent. | Dr. Paridhi Agrawal Dr. Pradnya Nikhade Department of endodontics, SPDC |
SPDC | November |
| 30 | Effect of musical therapy on salivary cortisol levels & oral health related quality of life in patients under prosthetic rehabilitation with fixed prosthesis – an in vivo study | Dr. Ankita Pathak Dr. Mithilesh Dhamande Department of Prosthodontics, SPDC |
SPDC | December |
| 31 | Study of ineffective erythropoiesis by elucidating ferrokinetics, apoptosis and hepcidin in transfusion dependent and independent beta thalassemia | Dr. Obaid Noman Dr. Arvind Bhake Department of Pathology, JNMC |
JNMC | December |
| JNMC | : 03 |
| SPDC | : 11 |
| MGAC | : 12 |
| DMCP | : 01 |
| OTHER | : 02 |
Discontinued |
02 |
List of Ongoing Research Projects 2023
| SN | Title of the project | Investigator |
| 1 | ICMR registry for rare diseases ICMR New Delhi (Haematology) |
Dr. Arvind Bhake Dr. Obaid Noman Department of Pathology, JNMC |
| 2 | Rifampicin extraction in Urine, estimation by HPLC | Shilpa Upadhyay Dr. Zahir Syed Quazi R & D, DMIMS(DU) |
| 3 | Comparative evaluation of polyherbal preparation as an adjuvant in metronomic chemotherapy in oral potentially malignant disease of moderate dysplasia – RCT | Dr. Rahul Bhowate Department of Oral Medicine & Radiology, SPDC |
| 4 | Gene polymorphism in ligamentous injury | Dr. Sanjay Deshpande Department of Orthopedics, JNMC |
| 5 | Standard drug release of Doxycycline and curcumin using electrospin nanofibers | Dr. Ashutosh Bagde Dr. Priyanka Banode, Dr. Zahir Quazi R & D |
| 6 | To Evauate dose dependent efficacy of antioxidant vit. C in relation to oxidative stress level in subjects with OSMF | Dr. Shraddha Patel Dr. Vidya Lohe Department of ODMR, SPDC |
| 7 | Assessment of efficacy of seasonal rutushodhan karma on oxidative stress in healthy volunteers | Dr. Pradnya Dandekar Dr. Vaishali Kuchewar Department of Kriyasharir, MGAC |
| 8 | Evaluation of effect of sharkara as anupana on the Bioavailability enhancer effect on Haritaki | Dr. Sneha Vidhate Dr. Dattatray Sarvade Department of Dravyaguna, MGAC |
| 9 | Evaluation and comparison of anxiety levels after using guided imagery technique for relaxation and modified guided imagery-hypnotherapy techniques in 6 to 14 year old children undergoing local anesthesia administration | Dr. Himani Parakh Dr. Nilima Thosar Department of pediatric and preventive Dentistry, SPDC |
| 10 | Evaluation of Anti-allergic activity of Panchashirishadi Agad in histamine induced allergy in Wistar rats | Dr. Shanti Manyala Dr. Sonali Chalakh Department of Agadtantra, MGAC |
| 11 | Comparative evaluation of novel Ca(OH)2 hydrogel with Ca(OH)2 iodofrom as obturating material : an in-vitro study | Dr. Dhruvi Raj Solanki Dr. Punit Fulzele Department of Pedodontics, SPDC |
| 12 | Comparative evaluation of Shatavari Ghanvati and Brahmi ghanavati in Senile Dementia | Dr. Mayuri Bawane Dr. Vaishali Kuchewar Department of kayachikitsa, MGAC |
| 13 | In vivo assessment of antihistaminic and anti-inflammatory action of Dooshivishari Agada | Dr. Sonali Chalakh Department of Agadtantra, MGAC |
| 14 | Study the effect of Nisha amalaki (as an adjuvant drug) in uncontrolled type II diabetes Mellitus – A Pragmatic controlled trial . | Dr. Shweta Parwe Department of Panchkarma MGAC |
| 15 | Standardization of molecular methods | Dr. Dipika Shaw Department of Microbiology, JNMC |
| 16 | ABX-464-106 Study | Dr. Vijendra Kirnake Department of Gastroenterology, JNMC |
| 17 | Characterization and identification of molecular prevalence in Kleb P & E.coli. from the clinical isolates from tertiary care center | Dr. Radha Kunjalwar Dr. Gargi Mudey Department of Microbiology, JNMC |
| 18 | A Comparative study to evaluate Vrishya karma of Ustrakantaka (Echinops echinatus Roxb.) seeds versus roots on testicular regenerative property in wistar albino rats | Dr. Monika Dr. Rajkumar Gupta Department of Dravyaguna, MGAC |
| 19 | Pharmaceutical development and analysis of Tripatra Parpati and evaluation of its acute toxicity and antidiarrheal activity in wistar albino rats | Dr. Yogi Tajne Dr. Bharat Rathi Department of Rasshastra, MGAC |
| 20 | Identification and quantification of growth factors in the growth and development of cartilage present in exosomes of lactating mother’s blood of cleft infant as compared to non cleft infant – an analytical observational study | Dr. Nikita Soni Dr. Priyanka Niranjane Department of Orthodontics, SPDC |
| JNMC | : 06 |
| SPDC | : 04 |
| MGAC | : 09 |
| R & D | : 02 |
| OTHER | : 00 |